Understanding Perimenopause Supplements: Navigating Through Transition
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Understanding Perimenopause Supplements: Navigating Through Transition

Perimenopause is the transitional phase leading up to menopause, marked by various physiological changes that can affect a woman's health and well-being significantly. This stage can start as early as the mid-30s to 40s and is characterized by fluctuating hormone levels, primarily estrogen and progesterone, which lead to a wide range of symptoms. Understanding these symptoms is crucial for managing them effectively. Here's a detailed look at the common and less well-known symptoms associated with perimenopause.

Common Symptoms of Perimenopause

  • Irregular Periods: One of the earliest signs of perimenopause is changes in menstrual cycle regularity. Periods may become erratic; they can be longer or shorter, lighter or heavier, or you might skip them altogether.
  • Hot Flashes and Night Sweats: These are sudden feelings of warmth, which are usually most intense over the face, neck, and chest. Hot flashes can also lead to night sweats and can severely disrupt sleep.
  • Sleep Disturbances: Many women experience trouble falling asleep, staying asleep, or waking up earlier than they would like. Sleep issues during perimenopause are often compounded by night sweats.
  • Mood Changes: Fluctuating hormone levels can cause heightened emotional responses, mood swings, irritability, and increased risk of depression.
  • Vaginal Dryness: Decreased estrogen levels can lead to a thinning of the vaginal walls, which may become less elastic and lubricated. This change can make sexual activity uncomfortable or painful and increase the risk of vaginal infections.
  • Decreased Libido: Hormonal changes can also lead to a decrease in sexual desire or arousal.
  • Urinary Issues: Perimenopause can increase the frequency of urination and raise the risk of urinary tract infections. Some women may experience urinary incontinence.

Less Common Symptoms

  • Breast Tenderness: Hormonal fluctuations can lead to periods of breast tenderness or swelling.
  • Increase in Cholesterol Levels: Changing hormone levels can affect lipid metabolism, leading to an increase in bad cholesterol (LDL) and a decrease in good cholesterol (HDL).
  • Joint and Muscle Pain: Some women report increased joint and muscle pain during this period, which is not directly linked to any physical exertion.
  • Weight Gain: Hormonal changes can lead to weight gain, especially around the abdomen. This weight is often difficult to lose and can affect overall health.
  • Memory Lapses: Some women may experience mild forgetfulness or concentration problems during perimenopause.
  • Hair Changes: Hormonal fluctuations can lead to changes in hair texture and volume, with some women experiencing hair thinning or increased facial hair.

Key Supplements for Perimenopause

As women seek ways to manage these changes, supplements have become a popular choice for alleviating symptoms without relying solely on hormone replacement therapy (HRT). Here, we explore the effectiveness and safety of various supplements during perimenopause.

  • Black Cohosh: Often used for its potential to reduce hot flashes and night sweats, black cohosh is a herb that has garnered attention in numerous studies. While some research indicates that black cohosh can be helpful, results are mixed, and it's essential to consider liver health before starting this supplement as it may pose risks to liver function.
  • Flaxseed: Rich in lignans, which have estrogenic properties, flaxseed is thought to help balance hormones and may alleviate mild menopause symptoms like night sweats. However, its effectiveness can vary, and not all studies support its use for vasomotor symptoms.
  • Calcium and Vitamin D: Bone health is a significant concern during perimenopause as declining estrogen levels can lead to bone density loss. Calcium and vitamin D are vital for maintaining bone health, with recommended daily intakes to prevent osteoporosis. While these nutrients are best obtained through diet, supplements may be necessary for some women to reach their daily targets.
  • Red Clover: Containing isoflavones, red clover has been studied for its potential to ease menopause symptoms due to its plant estrogen content. However, research results are mixed, and its long-term safety remains under debate.
  • Vitamin D: Beyond bone health, vitamin D is crucial for overall well-being and helps with calcium absorption. While sunlight is a natural source, supplementation may be needed, especially in individuals with limited sun exposure.
  • Ginseng: Known for its mood-boosting and sleep-enhancing properties, ginseng may improve the quality of life during perimenopause. However, evidence supporting its use for physical symptoms like hot flashes is limited.
  • St. John's Wort: Frequently used for managing mood swings and depressive symptoms, St. John's Wort can be particularly useful when combined with black cohosh. However, it can interact with numerous medications, including birth control pills and certain cancer treatments, so it's crucial to consult with a healthcare provider before starting.
  • DHEA: A hormone that declines with age, DHEA supplementation has been explored for its ability to improve sexual function and skin health during menopause. However, its effectiveness is mixed, and it carries potential risks, including an impact on hormone-sensitive cancers.

Safety and Considerations

When considering supplements for perimenopause, it's essential to discuss them with a healthcare provider. Supplements are not regulated by the FDA in the same way that medications are, which means their purity and potency can vary significantly between brands. Additionally, they can interact with other medications and have side effects that may not be immediately apparent.

Lifestyle Modifications

In addition to supplements, making lifestyle changes can significantly impact the severity of perimenopausal symptoms. Regular exercise, a balanced diet rich in fruits, vegetables, and whole grains, adequate hydration, and stress-reduction techniques like yoga and meditation can all help manage symptoms naturally.

Conclusion

While supplements can offer relief during perimenopause, they should be used judiciously and in conjunction with lifestyle changes. Always consult with a healthcare provider to tailor a treatment plan that considers personal health history and current medications. The journey through perimenopause is unique for every woman, and finding the right balance of treatments can take time and adjustment.

References
  • Elders, Petra JM, et al. "Long‐term effect of calcium supplementation on bone loss in perimenopausal women." Journal of Bone and Mineral Research 9.7 (1994): 963-970.
  • Barnhart, Kurt T., et al. "The effect of deydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, lipid parameters, and health-related quality of life." The Journal of Clinical Endocrinology & Metabolism 84.11 (1999): 3896-3902.
  • Huntley, Alyson L., and Edzard Ernst. "Soy for the treatment of perimenopausal symptoms—a systematic review." Maturitas 47.1 (2004): 1-9.
  • Taylor, Maida. "Alternative medicine and the perimenopause: an evidence-based review." Obstetrics and Gynecology Clinics 29.3 (2002): 555-573.
  • Szydłowska, I., et al. "Effects of probiotics supplementation on the hormone and body mass index in perimenopausal and postmenopausal women using the standardized diet. A 5-week double-blind, placebo-controlled, and randomized clinical study." European Review for Medical & Pharmacological Sciences 25.10 (2021).
  • Geller, Stacie E., and Laura Studee. "Botanical and dietary supplements for menopausal symptoms: what works, what does not." Journal of women's health 14.7 (2005): 634-649.
  • Amsterdam, Jay D., et al. "Randomized, double-blind, placebo-controlled trial of Cimicifuga racemosa (black cohosh) in women with anxiety disorder due to menopause." Journal of clinical psychopharmacology 29.5 (2009): 478-483.
  • Newton, Katherine M., et al. "Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial." Annals of internal medicine 145.12 (2006): 869-879.
  • Sant’Ana, Cíntia Tomaz, et al. "Brown and golden flaxseed reduce intestinal permeability and endotoxemia, and improve the lipid profile in perimenopausal overweight women." International Journal of Food Sciences and Nutrition 73.6 (2022): 829-840.
  • Luís, Ângelo, F. Domingues, and L. Pereira. "Effects of red clover on perimenopausal and postmenopausal women’s blood lipid profile: A meta-analysis." Climacteric 21.5 (2018): 446-453.
  • Abdali, Khadijeh, Marjan Khajehei, and Hamid Reza Tabatabaee. "Effect of St John's wort on severity, frequency, and duration of hot flashes in premenopausal, perimenopausal and postmenopausal women: a randomized, double-blind, placebo-controlled study." Menopause 17.2 (2010): 326-331.
  • Luna, Selva L., et al. "Lack of effect of short-term DHEA supplementation on the perimenopausal ovary." Biology of reproduction 103.6 (2020): 1209-1216.
IN THIS ARTICLE
1.Common Symptoms of Perimenopause
2.Less Common Symptoms
3.Key Supplements for Perimenopause
4.Safety and Considerations
5.Lifestyle Modifications
6.Conclusion